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Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

Eligible age

18+ yrs

Accepts

All genders

Locations

3 states

Healthy volunteers

No

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About this study

This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple types of immunotherapies, chemoimmunotherapy and tumor types.

Sponsor: Mayo Clinic

You may qualify if…

  • Subjects must meet one of the following criteria:
  • Subjects suspected of or diagnosed with the following Stage IV/metastatic or recurrent malignancies:
  • Lung: Non-small Cell Lung Cancer (NSCLC)
  • Skin: Cutaneous Malignancy, excluding Uveal Melanoma
  • Esophageal Cancer
  • Cervical Cancer
  • Endometrial Cancer
  • Colon Cancer: Mismatch repair deficient (dMMR) CRC only

You may not qualify if…

  • Pregnant women because this study involves a greater than minimal risk procedure (biopsy)
  • Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would make the patient inappropriate for entry into this study or interfere significantly with the proper assessment of safety for the biopsy
  • Immunocompromised patients and patients known to be HIV positive and currently receiving antiretroviral therapy
  • NOTE: Patients known to be HIV positive, but without clinical evidence of an immunocompromised state, are eligible for this trial
  • Uncontrolled intercurrent illness including, but not limited to:
  • ongoing or active infection
  • psychiatric illness/social situations that would limit compliance with study requirements
  • Subjects who are enrolled or plan to be enrolled in a blinded cancer therapeutic treatment trial

Where it's recruiting

Arizona

Phoenix

Florida

Jacksonville

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT06349642 · last updated 2026-03-12

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumo · TrialPath