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RecruitingPainSickle Cell Disease

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Eligible age

16–30 yrs

Accepts

All genders

Locations

11 states

Healthy volunteers

No

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About this study

The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.

Sponsor: University of Pittsburgh

You may qualify if…

  • 1. Aged 16 to 30 years of age at time of enrollment
  • 2. Sickle Cell Disease diagnosis of any genotype based on referral or documentation
  • 3. Reports chronic pain (≥4 days/week for past 3 months or more) OR A) Being prescribed pain medication to be taken (≥4 days/week for past 3 months or more) OR B) Taking pain medication (≥4 days/week for past 3 months or more) OR C) Receiving non-pharmaceutical pain treatment (≥4 days/week for past 3 months or more)
  • 4. Access to an iOS or Android mobile device with internet access

You may not qualify if…

  • 1. Unable to speak or read English
  • 2. Prior hematopoietic stem cell transplant for sickle cell disease

Where it's recruiting

Alabama

Mobile

California

Los Angeles

Connecticut

Hartford

Georgia

Atlanta

Illinois

Chicago

Michigan

Ann Arbor

New York

New York · Rochester

North Carolina

Durham · Greenville

Pennsylvania

Pittsburgh

Virginia

Richmond

Source: ClinicalTrials.gov · NCT06374238 · last updated 2026-01-07

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain · TrialPath