RecruitingARDSMechanical Power
Ventilatory Parameters in Predicting Outcomes in ARDS Patients
Eligible age
19–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This is a single-centre prospective observational study aimed to determine if Pocc (occlusion pressure at 100 msec), TCe ( Expiratory time constant ), Mechanical Stress power, Ventilatory ratio and C20/Cdyn would predict outcomes in patients with moderately severe ARDS (Acute respiratory distress syndrome), who are on mechanical ventilation
Sponsor: CentraCare
You may qualify if…
- ✓ Patients with Acute respiratory failure needing mechanical ventilation
- ✓ Diagnosis of Severe ARDS with severity: PF ratio \< 150, with PEEP/CPAP \> 5
You may not qualify if…
- ✕ r2 \< 0.95, monitored on the ventilator
- ✕ Expiratory flow that is not first-order or non-exponential decay
- ✕ Patients with Nor-epinephrine requirements \> 0.1 mcg/kg/min within 2 hours of intubation
- ✕ Patients requiring ECMO ( Extracorporeal membrane oxygenation)
- ✕ Patients with COPD or pulmonary fibrosis with a premorbid FEV1 \< 1.5 L
- ✕ Severe atherosclerotic vascular disease
- ✕ Patients with a chest tube, intra-abdominal hypertension or with its risk factors
- ✕ Patients with structural heart disease including pulmonary hypertension (RVSP \> 45) and heart failure
Where it's recruiting
Minnesota
Saint Cloud
Source: ClinicalTrials.gov · NCT06400095 · last updated 2024-08-22