RecruitingEndometriosis
Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy
Eligible age
18–45 yrs
Accepts
Women
Locations
0 states
Healthy volunteers
No
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About this study
This study aims to analyze the salivary miRNA specific for patients diagnosed with endometriosis, specifically evaluating the miRNA profile of patients who respond versus those who do not respond to progestin therapy. Ninety patients attending the Chronic Pelvic Pain Clinic will be recruited, and they will be asked to provide a saliva sample before starting medical therapy. The response to the therapy will be evaluated after 4 months from the beginning of the therapy itself.
Sponsor: University of Udine
You may qualify if…
- ✓ Age \> 18 years
- ✓ Fertile age
- ✓ Clinical-ultrasound diagnosis or histological diagnosis of endometriosis
- ✓ Informed consent
You may not qualify if…
- ✕ Pregnancy
- ✕ Pre-menarcheal or post-menopausal status
- ✕ Chronic pelvic pain syndrome with or without central sensitization assessed with the Central Sensitization Inventory Test (CSI)
- ✕ Neoplasia, diabetes, BMI \> 30 kg/m2, coagulopathies, autoimmune diseases, or other conditions that may affect salivary miRNA measurement
- ✕ Currently undergoing progestin therapy
Source: ClinicalTrials.gov · NCT06414720 · last updated 2025-04-02