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RecruitingMetabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Eligible age

18–75 yrs

Accepts

All genders

Locations

33 states

Healthy volunteers

No

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About this study

The study will assess the efficacy and safety of pegozafermin administered in participants with compensated cirrhosis due to MASH (biopsy-confirmed fibrosis stage F4 MASH \[previously known as nonalcoholic steatohepatitis, NASH\]).

Sponsor: 89bio, Inc.

Where it's recruiting

Alabama

Birmingham · Homewood

Arizona

Chandler · Flagstaff · Peoria · Phoenix

Arkansas

Little Rock · North Little Rock

California

Camarillo · Canoga Park · Coronado · Fountain Valley

Colorado

Littleton

Florida

Clermont · Fort Myers · Gainesville · Hialeah Gardens

Georgia

Athens · Atlanta

Illinois

Chicago

Indiana

Hammond · New Albany · South Bend

Iowa

Iowa City

Kansas

Kansas City · Topeka

Louisiana

Lafayette · Lake Charles · West Monroe

Source: ClinicalTrials.gov · NCT06419374 · last updated 2026-06-04