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RecruitingHeart Failure With Preserved Ejection FractionHeart Failure With Reduced Ejection FractionCardiovascular Diseases

Home-Based Cardiac Rehabilitation for Patients With Heart Failure

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important, many individuals will still not participate for a variety of reasons. This pilot randomized controlled trial is evaluating a home-based cardiac rehabilitation (HBCR) intervention delivered using a custom app and digital tools in patients with heart failure. After a brief roll-in period, participants are randomized to one of two groups: (1) control or (2) HBCR mobile health intervention. The intervention targets key health behaviors and includes traditional cardiac rehabilitation components. The study will assess the effect of the intervention on physical activity, quality of life, clinical events, and other outcomes.

Sponsor: Vanderbilt University Medical Center

You may qualify if…

  • 1. Stage C HF (NYHA Class I-III) AND
  • 1. Discharged from a HF hospitalization OR
  • 2. Scheduled for appointment in a cardiology clinic with a prior HF hospitalization within the past 12 months OR
  • 3. Scheduled for appointment in a cardiology clinic with a KCCQ-SS \<75
  • 2. Receives longitudinal HF care at VUMC, including at least one visit prior to the roll-in phase
  • Randomized Controlled Trial (beyond roll-in phase)
  • 1\. Willingness to continue and participate in the study visits and other study activities required for the RCT

You may not qualify if…

  • 1. Unwilling or unable to provide informed consent for participation in the RCT
  • 2. Requires a wheelchair all (or most) of the time inside and outside the house; it is acceptable if a wheelchair is needed, for example, for parking lot transfer for a clinic visit and navigating around the hospital without it being needed in the home
  • 3. If an individual uses a walker or cane all (or most) of the time, then he/she will be excluded if he/she scores 2 or lower on the Mini-Cog or the patient is unable to perform 2 chair sit-to-stands independently or is deemed to be at high fall risk during baseline visit assessment.
  • 4. History of falls over the last 6 months; an isolated explainable fall with no injury would not exclude the patient, but a tendency to falls indicative of balance/stability issues would exclude the patient.
  • 5. Age \< 18 years
  • 6. Stage D HF (advanced HF under evaluation for LVAD or transplant)
  • 7. NYHA class IV symptoms
  • 8. Congenital heart disease

Where it's recruiting

Tennessee

Nashville

Source: ClinicalTrials.gov · NCT06479876 · last updated 2025-09-24