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RecruitingSpinal Cord Injury CervicalSpastic

Task Practice and Spinal Cord Stimulation

Eligible age

22–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this study is to understand the effects of combined task practice with transcutaneous cervical spinal cord stimulation. The study will explore the effect of higher stimulation frequencies on spasticity. Transcutaneous stimulation has been shown to improve motor function in some individuals with chronic spinal cord injury. The study intends to explore scientifically the association between higher stimulation frequencies and spasticity/hypertonicity.

Sponsor: University of Miami

You may qualify if…

  • ✓ 22-70 years of age
  • ✓ Non-progressive cervical spinal cord injury
  • ✓ Minimum 12 months year post-injury.
  • ✓ American Spinal Injury Association (ASIA) Impairment Scale (AIS) classification B, C, or D.
  • ✓ Able to take part in upper extremity therapy procedures.
  • ✓ GRASSP-Prehension score ≥10.
  • ✓ MAS Score ≥3 but \<6 in at least one arm.
  • ✓ Can commit to the time required for the study.

You may not qualify if…

  • ✕ Has any unstable or significant medical condition that is likely to interfere with study procedures like severe neuropathic pain, depression, mood disorders, or other cognitive disorders.
  • ✕ Has uncontrolled cardiopulmonary disease or cardiac symptoms.
  • ✕ Requires ventilator support.
  • ✕ Has been diagnosed with autonomic dysreflexia that is severe, unstable, and uncontrolled.
  • ✕ Has an autoimmune etiology of spinal cord dysfunction/injury
  • ✕ Previously diagnosed as having transverse myelitis
  • ✕ History of additional neurologic diseases such as stroke, multiple sclerosis, traumatic brain injury, epilepsy or history of seizures.
  • ✕ Peripheral neuropathy (diabetic polyneuropathy, entrapment neuropathy, etc.)

Where it's recruiting

Florida

Miami

Source: ClinicalTrials.gov · NCT06494020 · last updated 2025-08-19