RecruitingObesityWeight GainBariatric Surgery Candidate
Exercise, Brain Activity, and Weight Maintenance
Eligible age
18–70 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
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About this study
This study aims to explore how HIIT influences brain function, neural and molecular pathways related to weight control, setting the stage for future obesity intervention research.
Sponsor: Joslin Diabetes Center
You may qualify if…
- ✓ Age 18-70 years
- ✓ Body mass index (BMI) \>19 kg/m2 and body weight\< 250kg
- ✓ Participants must have experienced a clinically significant weight regain, defined as over 10% of their maximum weight lost, within 1 to 5 years following their bariatric surgery. They will be asked to self-report their weight loss history. Participants must also provide the operative report from their bariatric surgery for reference.
- ✓ In good general health with no conditions that could influence the outcome of the trial, and in the judgment of the investigator is a good candidate for the study based on review of available medical history, physical examination and clinical laboratory evaluations
- ✓ Willing to adhere to the protocol requirements for the duration of the study
You may not qualify if…
- ✕ Type 1 diabetes mellitus
- ✕ Peripheral neuropathy with insensate feet
- ✕ Recent blood donation within the last 2 months
- ✕ Use of beta-blockers
- ✕ Current pregnancy or breastfeeding
- ✕ Active Heart or lung disease
- ✕ Severe hypertension (systolic \>160 mmHg or diastolic \>90 mmHg)
- ✕ Inability to exercise for any reason
Where it's recruiting
Massachusetts
Boston
Source: ClinicalTrials.gov · NCT06511310 · last updated 2025-09-04