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RecruitingAlzheimer DiseaseMild Cognitive ImpairmentDementia

Study to Understand Novel Biomarkers in Researching Dementia

Eligible age

60+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to determine the relationships between amyloid, tau, and neurodegeneration biomarkers in the blood and the presence of Alzheimer's disease (AD) pathology, clinical cognitive decline, and diagnosis. We aim to understand how well blood-based biomarkers can diagnose and predict Alzheimer's disease, which will help to further develop and validate blood tests for the disease.

Sponsor: Washington University School of Medicine

You may qualify if…

  • At least 60 years of age
  • 80% of the newly enrolled clinic-based cohort will have symptoms of forgetfulness, mild cognitive impairment, mild dementia, or Alzheimer's disease as determined by their medical chart and/or provider
  • All SEABIRD participants will be invited to participate regardless of their cognitive status

You may not qualify if…

  • Unable to perform one or more basic activities of daily living (eating, bathing, dressing, ambulating, toileting) due to cognitive impairment
  • Uncontrolled hepatitis B, hepatitis C, or HIV at time of blood collection
  • Taking a disease-modifying drug for AD at time of enrollment
  • Blood transfusion in the last three months
  • Unwilling or unable to participate in all study activities

Where it's recruiting

Missouri

St Louis

Source: ClinicalTrials.gov · NCT06547099 · last updated 2026-01-16