RecruitingHealthyObesity
Growth Hormone Resistance of Beta-cells in People With a Family History of Type 2 Diabetes
Eligible age
18–59 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a family history of type 2 diabetes at the University of Missouri. Our aim is to advance understanding of how growth hormone affects beta-cells and risk factors for developing type 2 diabetes.
Sponsor: University of Missouri-Columbia
You may qualify if…
- ✓ 18 to 59 years old
- ✓ body mass index ≥30.0 kg/m2 and \<45.0 kg/m2
- ✓ Additional, group-specific inclusion criteria:
- ✓ Family history of type 2 diabetes: first degree relative with type 2 diabetes
- ✓ Control group: no family history of type 2 diabetes
You may not qualify if…
- ✕ Pregnant, planning to become pregnant during the study, or breastfeeding
- ✕ Current diagnosis or history of type 1 or type 2 diabetes
- ✕ Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)
- ✕ History of bariatric surgery
- ✕ Known, uncontrolled hypothyroidism
- ✕ History of intracranial hypertension, including papilledema, or a condition that increases the risk of developing intracranial hypertension, such as Turner Syndrome, Prader-Willi Syndrome, or renal impairment
- ✕ Current cancer or cancer that has been in remission less than 5 years
- ✕ First degree relative with type 1 diabetes diagnosis
Where it's recruiting
Missouri
Columbia
Source: ClinicalTrials.gov · NCT06571500 · last updated 2026-05-11