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RecruitingCOPD

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Eligible age

18–100 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Sponsor: University of Miami

You may qualify if…

  • Able to consent
  • Age 18 years or older
  • Diagnosis of COPD
  • Ability to ambulate without assistance
  • Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all

You may not qualify if…

  • Pregnancy
  • Being on bedrest
  • Inability to consent or cooperate with the study
  • Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
  • Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
  • Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)

Where it's recruiting

Florida

Miami

Source: ClinicalTrials.gov · NCT06578156 · last updated 2026-06-22

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD · TrialPath