RecruitingNeurogenic Detrusor OveractivitySpinal Cord Injuries
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
Eligible age
18–75 yrs
Accepts
All genders
Locations
4 states
Healthy volunteers
No
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About this study
This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A in male and female adult participants with Neurogenic Detrusor Overactivity (NDO)-related incontinence following Spinal Cord Injury (SCI), who have persistent incontinence after standard of care therapy and who perform Clear Intermittent Catheterization (CIC) on a regular basis.
Sponsor: EG 427
Where it's recruiting
Source: ClinicalTrials.gov · NCT06596291 · last updated 2026-02-05