RecruitingObesity
Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
Eligible age
18–45 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
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About this study
The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin sensitivity in men and women.
Sponsor: AdventHealth Translational Research Institute
You may qualify if…
- ✓ 1. Men and pre-menopausal women;
- ✓ 2. 18-45 years of age;
- ✓ 3. BMI 30.0-40.0 kg/m2;
- ✓ 4. For women, if not using pharmaceutical (hormonal) contraception (i.e. birth control pills, vaginal ring, injections, or implant), must agree to use either a double barrier method as a form of birth control to prevent pregnancy (i.e. male condom with spermicide, with or without cervical cap or diaphragm); use implants or intrauterine contraceptive devices; have a tubal ligation (surgically sterile); practice abstinence; or be in an established relationship with a vasectomized or same sex partner during the entire duration of the study;
- ✓ 5. Able to speak and understand written and spoken English;
- ✓ 6. Sedentary defined as self-reporting no more than 1 day per week, lasting no more than 60 minutes, of regular (structured) endurance or resistance exercise in the past year.
- ✓ 7. Must be willing to be randomized to either study group;
- ✓ 8. Must be willing to adhere to all study procedures.
You may not qualify if…
- ✕ 1. Self-reported unstable body weight in the last 3 months (\> ±5%);
- ✕ 2. Significant changes in the quality of the diet or the level of physical activity within the last 3 months;
- ✕ 3. Weight \>396 lb (180 kg);
- ✕ 4. Diagnosis of Type 1 or Type 2 diabetes mellitus;
- ✕ 5. Fasting blood glucose ≥126 mg/dL;
- ✕ 6. HbA1c ≥ 6.5%
- ✕ 7. Blood pressure \>140/90 mmHg ;
- ✕ 8. Self-reported history or presence of the following cardiovascular conditions: congestive heart failure, coronary artery disease, significant valvular disease, congenital heart disease, serious arrhythmia, stroke, symptomatic peripheral artery disease, stable angina, myocardial infarction or coronary revascularization within 6 months; clinically significant abnormalities on ECG, presence of cardiac pacemaker, or implanted cardiac defibrillator; inability to complete the VO2max test;
Where it's recruiting
Source: ClinicalTrials.gov · NCT06602141 · last updated 2026-03-27