RecruitingChronic Granulomatous Disease (CGD)

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

Eligible age

All ages

Accepts

All genders

Locations

49 states

Healthy volunteers

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

Check my eligibility →

About this study

This research study is designed to assess the prevalence of specific antibodies and inflammatory cytokines in adult and pediatric participants with CGD.

Sponsor: Ensoma

You may qualify if…

✓ The participant must have been diagnosed with CGD based on the referring physician's confirmation that NADPH oxidase activity is ≤5% (i.e., the percentage of dihydrorhodamine-positive \[DHR+\] cells is ≤5% by flow cytometry) OR based on confirmed pathogenic mutation in a CGD associated gene (CYBB, CYBA, NCF1, NCF2, NCF4, or CYBC1).
✓ The participant or the participant's legally authorized guardian or representative (if applicable) must be capable of giving signed informed consent.
✓ The participant (with assistance from the participant's legally authorized guardian/representative or primary caregiver, if applicable) must be capable of complying with the requirements and restrictions listed in the protocol and informed consent form (ICF).

You may not qualify if…

✕ The participant has undergone an allogeneic bone marrow transplant or investigational gene therapy.
✕ The participant is unable to comply with the sample collection procedure based on investigator judgment.