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RecruitingOverweight/ObesityStress

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Eligible age

18–75 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to learn more about how common lifestyle interventions, such as exercise, affect how our brains respond to performing thinking tasks and to viewing pictures of foods and various other objects. The investigators are also interested in how changes in hormones that might be different in men and women could affect how lifestyle interventions change these brain responses.

Sponsor: VA Office of Research and Development

You may qualify if…

  • ✓ Veteran
  • ✓ Body mass index (BMI) of 25 or greater
  • ✓ Physically inactive
  • ✓ Able to attend study visits in person in Aurora, CO

You may not qualify if…

  • ✕ Currently pregnant
  • ✕ History of bariatric surgery
  • ✕ Current eating disorder
  • ✕ Current treatment with appetite-altering medications (e.g., glucagon-like peptide-1 (GLP-1) agonists)
  • ✕ Contraindication to MRI (weight \> 500 pounds (lbs); claustrophobia; metal or electronic devices in the body)
  • ✕ Cardiovascular disease, chronic kidney disease, pulmonary disease, or diabetes
  • ✕ Unable to exercise due to cardiac, pulmonary, neurologic, or orthopedic reasons

Where it's recruiting

Colorado

Aurora

Source: ClinicalTrials.gov · NCT06627569 · last updated 2026-10-05