Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
The goal of this clinical trial is to learn if a treatment for adults with PTSD called prolonged exposure + incentives (PE+) works to treat pregnant patients. The main question it aims to answer is: Does PE+ decrease PTSD symptoms? All participants will receive PE+ to see if their PTSD symptoms at the end of the trial are less than at the beginning. Participants will: * Receive individual PE+ therapy for 1 hour weekly for 12 weeks. * Receive financial incentives for attending each PE+ session. * Attend assessment visits every 4 weeks for the 12 weeks of the trial. * Allow research staff to collect some information about their labor and delivery from their medical records after their babies are born.
Sponsor: University of Vermont
You may qualify if…
- ✓ Female
- ✓ \>18 years old
- ✓ Gestational age ≤ 25 weeks
- ✓ Meet current DSM-5 posttraumatic stress disorder criteria based on the Clinician Administered PTSD Scale for DSM-5
- ✓ Participants receiving psychotropic medications must be maintained on a stable dose for \>14 days prior to enrollment.
You may not qualify if…
- ✕ Male
- ✕ Under 18 years old
- ✕ Gestational age \> 25 weeks
- ✕ No current diagnosis of PTSD
- ✕ Current delusions or hallucinations, unstable bipolar disorder, imminent risk for suicide as assessed by the Mini International Neuropsychiatric Interview
- ✕ Enrolled in another ongoing evidence-based treatment for PTSD.
Where it's recruiting
Burlington
Source: ClinicalTrials.gov · NCT06670079 · last updated 2026-05-13