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RecruitingObesity

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

Eligible age

18–65 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this clinical trial is to investigate whether a Ketogenic Diet (KD) can increase Total Energy Expenditure (TEE), while benefiting appetite, during weight loss maintenance in reduced-obese individuals.

Sponsor: University of Alabama at Birmingham

You may qualify if…

  • BMI 30-45 kg/m2
  • Both men and women
  • Age between 18-65 years
  • Sedentary to moderately active (\<2 h/wk of moderate, structured, intentional, exercise)

You may not qualify if…

  • Pregnancy or lactation
  • Daily use of tobacco (\>1 pk/wk)
  • Change in weight greater than 5 lb in the previous 3 months
  • Cognitive impairment
  • Previous bariatric surgery
  • History of eating disorder
  • Presence of any condition (e.g. DM2, PCOS, inflammatory disease, untreated thyroid disease, fluid overload states such as chronic kidney disease, congestive heart failure, or cirrhosis)
  • Use of any medication (e.g., glucocorticoid, GLP-1 analogues, hormone replacement therapy) deemed to interfere with study outcomes.

Where it's recruiting

Alabama

Birmingham

Source: ClinicalTrials.gov · NCT06736028 · last updated 2026-04-07