RecruitingMenopauseHot FlashesBlood Pressure Regulation
Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training
Eligible age
45–60 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve activity and sleep.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ Females aged 45-60 with hot flashes.
- ✓ Participants will be recruited from Rochester, MN and surrounding areas.
- ✓ Non-smokers.
- ✓ BMI \< 40kg/m\^2.
- ✓ No history of cardiovascular disease, except for hypertension.
You may not qualify if…
- ✕ Detailed medical and social histories will be collected. To allow for ecological validity, participants will not be excluded for use of menopausal hormone therapy or medications affecting cardiovascular function so long as they have been on a consistent regimen for ≥3 months and during the study period. This approach to medications is consistent with recent work in this area.
- ✕ Participants will be screened for contraindications to inspiratory muscle strength training including, a history of spontaneous pneumothorax, collapsed lung that has not healed fully, a perforated eardrum that has not healed fully, and/or any other condition of the eardrum.
- ✕ Additional exclusion criteria will include the use of sleep aids (i.e., prescription, melatonin, doxylamine, valerian root, etc.).
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT06743269 · last updated 2026-03-30