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RecruitingObesity and OverweightInsulin ResistanceObesity and Obesity-related Medical Conditions

New Mechanisms of Obesity

Eligible age

15–22 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

Given the pervasiveness of Pediatric Obesity, it is imperative to understand its pathophysiology and develop alternative strategies to reverse this condition. Herein, investigators propose to elucidate the interaction between colonic fermentation and insulin resistance in modulating metabolism in youth with obesity.

Sponsor: Yale University

You may qualify if…

  • Age 15 to 22 years
  • In puberty (girls and boys: Tanner stage III-V);
  • BMI \>85th

You may not qualify if…

  • Pregnancy;
  • endocrinopathies (e.g., Cushing syndrome);
  • substance abuse;
  • medications affecting insulin resistance such as metformin, GLP-1 analogues; -
  • high fibers intake (\> 30g/day) as assessed by a 3-day food record.

Where it's recruiting

Connecticut

New Haven

Source: ClinicalTrials.gov · NCT06768827 · last updated 2026-01-28

New Mechanisms of Obesity · TrialPath