RecruitingHIVDepressionCannabis Use Disorder
Stress and Pain in People Living With HIV
Eligible age
18–68 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task (YPST) and follow-up phase to assess drug use and mood symptoms.
Sponsor: Yale University
You may qualify if…
- ✓ good health as verified by screening examination
- ✓ Able to read English and complete study evaluations and provide informed written and verbal consent. Additional criteria PLWH
- ✓ HIV-1 lab test positive
- ✓ undetectable viral load
- ✓ good ART adherence
- ✓ Additional criteria by group:
- ✓ PLWH +CM:
- ✓ CB positive urine toxicology
You may not qualify if…
- ✕ meet primary, current moderate and severe criteria for other SUD including cocaine, alcohol, opiates, sedatives, nicotine
- ✕ current use or past history of cocaine or opioid use disorder
- ✕ history of any psychotic disorder
- ✕ current diagnoses of bipolar disorder and PTSD
- ✕ psychotic or otherwise severely psychiatrically disabled (i.e., suicidal, homicidal, current mania)
- ✕ significant underlying medical conditions such as cerebral, renal, thyroid or cardiac pathology that would interfere with study participation
- ✕ medications with known central effects on HPA axis and cytokines/immune function
- ✕ women who are pregnant, nursing or those using hormonal birth control that affect HPA axis cortisol responses.
Where it's recruiting
Connecticut
New Haven
Source: ClinicalTrials.gov · NCT06784908 · last updated 2026-04-27