PEDI Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcus Study
Eligible age
3–17 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
No
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About this study
The objective of the Pediatric Epidemiological Data and Incidence (PEDI) PANDAS study is to demonstrate the feasibility of enrollment and retention of subjects in a study to determine the incidence and natural history of children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) with regard to spectrum, course and outcome. The investigators aim to demonstrate they can recruit and retain 85% of children who are eligible for this study. Eligible children are those who fit criteria for PANS and Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS). Each child will be followed for one year.
Sponsor: University of Wisconsin, Madison
You may qualify if…
- ✓ Child age 3-17 years old
- ✓ Child and their parent/guardian are able to complete all study activities in English
- ✓ Potential participant's family plans to be followed within UW Health or Dartmouth Health for at least one year
- ✓ Pediatric patient who is a current member of the primary care population at either UW Health or Dartmouth Health
- ✓ Abrupt onset of symptoms (within 7 days) occurring in the past 3 months. Willing to come in-person for at least the baseline visit.
- ✓ Suspected diagnosis of PANS or PANDAS based on published criteria:
- ✓ PANS: (A) Abrupt, dramatic, overnight onset of obsessive compulsive disorder (OCD) or severely restricted food intake; (B) concurrent abrupt onset of additional severe neuropsychiatric symptoms from at least 2 of the following 7 categories:
- ✓ 1. Anxiety
You may not qualify if…
- ✕ History of tics, OCD or food restriction/avoidance that contradicts a history of sudden onset or was present before the onset of this investigation
- ✕ Current symptom(s) of Pica
- ✕ Previous participation in the study
- ✕ Not suitable for study participation at the discretion of the site investigator (e.g., the child does not have verbal or cognitive ability adequate for self-report assessment)
- ✕ Patient or family is unable to complete the study questionnaires or procedures in English as the primary language
Where it's recruiting
Lebanon
Madison
Source: ClinicalTrials.gov · NCT06811935 · last updated 2026-01-27