RecruitingProstate Cancer
Evaluating Tolerability of ePUHRT With Brachytherapy Boost
Eligible age
18+ yrs
Accepts
Men
Locations
1 state
Healthy volunteers
No
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About this study
The purpose of this study is to evaluate the tolerability and toxicity of combining two radiation therapy methods for prostate cancer: Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT), which is an external beam radiotherapy with High Dose Rate Brachytherapy Boost (form of internal radiation where a cancer doctor implants a small plastic tube or balloon (catheter) in the tumor).
Sponsor: Indiana University
You may qualify if…
- ✓ 1. ≥ 18 years old at the time of informed consent
- ✓ 2. Capable of providing informed consent and HIPAA authorization
- ✓ 3. Karnofsky performance score ≥ 70
- ✓ 4. Pathologically confirmed unfavorable intermediate, high, and very high-risk prostate cancer per treating physician
- ✓ 5. Candidate plans to undergo the standard of care prostate high dose brachytherapy boost procedure
You may not qualify if…
- ✕ 1. Prior pelvic irradiation treatment
- ✕ 2. Prior rectal surgery which precludes instrumentation with rectal ultrasound probe.
- ✕ 3. Evidence of nodal or distant disease on screening diagnostic work up.
- ✕ 4. Prior prostatectomy, Holmium laser enucleation of the prostate or transurethral resection of the prostate procedure
- ✕ 5. International Prostate Symptom Score (IPSS) score \> 16 despite medical therapy
Where it's recruiting
Indiana
Indianapolis
Source: ClinicalTrials.gov · NCT06817668 · last updated 2025-09-26