RecruitingMajor DepressionSleep
Sleep TMS for Depression
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.
Sponsor: Stanford University
You may qualify if…
- ✓ Adults ages 18-65 years
- ✓ Current Major Depressive Disorder (MDD) diagnosis
- ✓ Failed ≥1 antidepressant medication
- ✓ Moderate-to-severe depression
- ✓ Stable antidepressant medication dose for ≥ 6 weeks prior to enrollment
- ✓ Healthy control participants are adults ages 18-65 years without current MDD symptoms, not taking antidepressant or antipsychotic medications, and without major psychiatric, neurological, substance use, medical conditions affecting brain function, or TMS/MRI contraindications.
You may not qualify if…
- ✕ Intellectual disability
- ✕ Significant head injury/neurological disorder
- ✕ Pregnancy or postpartum
- ✕ TMS/MRI contraindications
- ✕ Active substance use/suicidal ideation
Where it's recruiting
California
Stanford
Source: ClinicalTrials.gov · NCT06824415 · last updated 2026-06-23