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RecruitingSupra-sacral Spinal Cord InjurySpinal Cord InjuryUrinary Incontinence

CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI). Participants will take Epidiolex (purified CBD) for 90 days

Sponsor: University of Wisconsin, Madison

You may qualify if…

  • \>18 years of age
  • History of supra-sacral spinal cord injury of any mechanism
  • Urinary incontinence with ≥2 episodes of urinary incontinence per day (outside of spinal shock)
  • Willingness to participate in drug intervention trial
  • English-speaking (able to provide consent and complete questionnaires)

You may not qualify if…

  • History of intravesical Botox
  • Actively taking \>15 mg of Oxybutynin single dose or equivalent dose of alternative anticholinergic medication for bladder symptoms
  • Use of Cannabis (any form) outside of study as determined by urine drug screen after washout period of 1 month if prior Cannabis use reported
  • Thought or mood disorder aside from depression

Where it's recruiting

Wisconsin

Madison

Source: ClinicalTrials.gov · NCT06840899 · last updated 2026-03-04