Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
Eligible age
18–39 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The AYA WELL study is a 2-arm randomized clinical trial to test the efficacy of a theory-based, mHealth weight management intervention adapted specifically for adolescent and young adult cancer survivors compared to a self-guided arm. Participants, diagnosed with cancer between ages 15-39, currently age 18-39, post-treatment at least 6 months, and who have overweight or obesity will be randomized to receive either: 1) a comprehensive mHealth weight management program (intervention) or 2) digital tools + health education + peer support (self-guided) over 12 months. Outcomes will be assessed at 3, 6, and 12 months.
Sponsor: UNC Lineberger Comprehensive Cancer Center
You may qualify if…
- ✓ 18-39 years old at the time of consent.
- ✓ Diagnosed with first invasive cancer between ages 15-39 years (self-report).
- ✓ Within 10 years of diagnosis with no evidence of progressive disease or second primary cancers (self-report).
- ✓ Completed active cancer directed therapy (cytotoxic chemotherapy, radiation therapy and/or definitive surgical intervention) at least six months prior to enrollment; may be receiving "maintenance" therapy to prevent recurrences (self-report).
- ✓ Body mass index (BMI) of 25-50 kg/m2
You may not qualify if…
- ✕ Type 1 diabetes or currently receiving certain medical treatments for Type 2 diabetes
- ✕ Report a history of heart attack or stroke within previous 6 months
- ✕ Health problems which preclude ability to walk for physical activity (e.g., lower limb amputation). Participants endorsing items 1-4 on the Physical Activity Readiness Questionnaire (PAR-Q) (experience of heart problems, frequent chest pains, or faintness or dizziness) will be excluded from the study.
- ✕ Lost 5% or more of body weight (and kept it off) in the last 3 months
- ✕ Lifetime history of clinical diagnosis or treatment of eating disorder (anorexia nervosa or bulimia nervosa), OR report of compensatory behaviors within the previous 3 months. If participant reports a history of compensatory behaviors, the investigators will review their information to determine eligibility.
- ✕ Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 12 months
- ✕ Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
- ✕ Hospitalization for depression or other psychiatric disorder within the past 12 months.
Where it's recruiting
Chapel Hill
Source: ClinicalTrials.gov · NCT06848491 · last updated 2026-03-23