RecruitingDiabetesWeight Loss
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
Eligible age
20–75 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.
Sponsor: University of Florida
You may qualify if…
- ✓ Between age: 20-75 yrs, English speaking, Physically mobile
- ✓ Body Mass Index (BMI) \>35 kg before surgery
- ✓ Compatible of MRI Scanning
- ✓ Willing to give a small blood sample
- ✓ Capable of providing informed consent
You may not qualify if…
- ✕ Prior or current neurological disorder
- ✕ Major psychiatric disturbance
- ✕ Unstable medical conditions (cancer)
- ✕ MRI contraindications (claustrophobia, metal implants, waist/torso circumference)
Where it's recruiting
Florida
Gainesville
Source: ClinicalTrials.gov · NCT06861790 · last updated 2026-02-10