RecruitingIntolerance of UncertaintyAnxietyIntolerance of Uncertainty; Anxiety
Test of Target Engagement of Ambiguity Aversion
Eligible age
25–60 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.
Sponsor: Northwestern University
You may qualify if…
- ✓ 1. Ages 25 to 60
- ✓ 2. Right-handed
- ✓ 3. Ability to read and write English
- ✓ 4. Capacity to provide informed consent
- ✓ 5. Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)
You may not qualify if…
- ✕ 1. Personal history of psychosis, mania, or hypomania
- ✕ 2. Personal history of autism spectrum disorder
- ✕ 3. IQ \< 80 as determined by the Wechsler Test of Adult Reading
- ✕ 4. Head injury with greater than 120 seconds loss of consciousness
- ✕ 5. Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
- ✕ 6. Currently pregnant
- ✕ 7. Use of any implanted electrical device (e.g., pacemaker, spinal stimulator, vagal nerve stimulator, Inspire sleep apnea device, etc.).
Where it's recruiting
Illinois
Chicago
Source: ClinicalTrials.gov · NCT06962527 · last updated 2026-05-26