Community-based Approach to Lowering Stress Through Mindfulness
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms? * Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control? * Is the intervention acceptable, appropriate, and feasible as delivered in a community setting? Participants will: * Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation. * Complete surveys online * Have their blood pressure measured with a non-invasive blood pressure cuff * Attend 1 focus group (optional)
Sponsor: Northwestern University
You may qualify if…
- ✓ ≥18 years old
- ✓ Lives, works, or spends much of their time in the South Side of Chicago neighborhood
- ✓ Self-reports diagnosis of hypertension or high blood pressure by a clinician
- ✓ Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
- ✓ Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported
You may not qualify if…
- ✕ \<18 years old
- ✕ Severe mental illness (e.g., bipolar disorder, psychosis)
- ✕ Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
- ✕ Unable to provide informed consent or complete study activities in English
Where it's recruiting
Chicago
Source: ClinicalTrials.gov · NCT06987799 · last updated 2026-04-13