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RecruitingHealthy AgingAlzheimer's Disease (AD)

Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Eligible age

60–75 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is critical for multi-tasking in daily life. The proposed research investigates whether playing a web-based cognitive complex game (the Breakfast Game) impacts cognitive performance in cognitively healthy older adults. To be enrolled in the study, participants will be asked to undergo a cognitive sassessment, health questionnires, and a blood exam. The intervention consist in one educational session on healthy aging, and 10 one-hour cognitive training sessions 2-3 times a week over one month. Participants will be asked to repeat the cognitive assessment within 1-2 weeks after the intervention, and after three months.

Sponsor: Rutgers, The State University of New Jersey

You may qualify if…

  • Age 60-75
  • Adequate English proficiency
  • Willingness to adhere to training protocol:
  • Attend 2 in-person assessments
  • Attend a blood test
  • Attend online intervention sessions and online follow-up assessment

You may not qualify if…

  • Low test scores (below 26 on the Montreal Cognitive Assessment)
  • Known history of cognitive impairment, dementia, stroke, seizure disorder, or other neuropsychiatric condition judged to impact cognitive performance.
  • Taking medications known to influence cognitive performance.
  • Sensory (e.g. visual, auditory) or physical (e.g. severe arthritic, orthopedic, neurologic) impairment incompatible with use of a standard computer workstation.
  • Enrolled in a concurrent study that could affect the outcome of this study.

Where it's recruiting

Source: ClinicalTrials.gov · NCT06995638 · last updated 2025-12-15