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RecruitingLow Back PainKnee Osteoarthritis

Ischemic Preconditioning in Osteoarthritis and Back Pain

Eligible age

50+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

Sponsor: University of Illinois at Chicago

You may qualify if…

  • Reported Knee Pain using ACR Criteria
  • Reported Back Pain using ODI Criteria \> 12
  • Ability to walk for at least 3 minutes without the use of aids
  • Ability to provide written informed consent

You may not qualify if…

  • Younger than 50 years old
  • History of Knee or Hip Replacements
  • History of steroid injection within the previous 6 months
  • Presence of neuromuscular joint condition that affects lower extremity function
  • History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
  • History of heart failure or thrombosis
  • Allergic to ultrasound gel
  • History of spine surgery

Where it's recruiting

Illinois

Chicago

Source: ClinicalTrials.gov · NCT07003113 · last updated 2025-11-17