Physical Capacity Building for Chronic Stroke
Eligible age
18–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery. Investigators believe that individuals who have had a stroke need to be treated similarly. Investigators will study the effects of a comprehensive modified cardiac rehabilitation program to determine if it can improve some of the physical and psychosocial problems common in survivors of stroke with and without depression.
Sponsor: Medical University of South Carolina
You may qualify if…
- ✓ Age 18-80
- ✓ A diagnosis of stroke at least 6 months prior
- ✓ Residual paresis in the lower extremity (Fugl-Meyer lower extremity \[LE\] motor score \<34)
- ✓ Ability to walk without assistance and without an AFO during testing and training at speeds ranging from 0.2-1.0 m/s
- ✓ Ability to follow instructions, complete cognitive testing and to communicate exertion, pain and distress
- ✓ No antidepressant medications or no change in doses of psychotropic medication for at least 4 weeks prior to the study (6 weeks if newly initiated medication)
- ✓ HDRS17 question #3 and PHQ-9 question #9 regarding suicide ≤ 2
- ✓ Provision of informed consent.
You may not qualify if…
- ✕ Unable to ambulate at least 150 feet or experienced intermittent claudication while walking
- ✕ Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's
- ✕ Dementia
- ✕ Life expectancy \<1 yr
- ✕ History of DVT or pulmonary embolism within 6 months
- ✕ Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
- ✕ Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest
- ✕ Attempt of suicide in the last 2 years or suicidal risk assessed by depression screening
Where it's recruiting
Charleston
Source: ClinicalTrials.gov · NCT07039305 · last updated 2025-12-08