RecruitingEndometrial CarcinomaEndometrial High Grade Endometrioid AdenocarcinomaStage II Endometrial Cancer
Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This study seeks to better understand the recurrence of high-risk endometrial cancer. It will collect information about cancer genetics to find out various hereditary or cancer specific genetic variants that may have a role in diagnosis or management and prognosis of cancer. It also seeks to develop a genetic results and medical record databank for future studies.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ Age ≥ 18 years
- ✓ Planned complete surgical staging at Mayo Clinic. Complete surgical staging includes at least total hysterectomy, bilateral salpingo-oophorectomy and lymph node assessment. Sentinel node mapping meets the criteria for lymph node assessment. Peritoneal cytology is recommended. Additional staging procedures such as pelvic and para-aortic nodal evaluation, omental biopsy or omentectomy, may also be utilized for staging in patients based on the clinical situation and at the surgeon's discretion
- ✓ At least one preoperative or postoperative feature of aggressive disease \[International Federation of Gynecology and Obstetrics (FIGO) staging used throughout this protocol\]
- ✓ Preoperatively:
- ✓ Biopsy with grade 3 endometrioid endometrial cancer (EC) or non-endometrioid EC
- ✓ Patients with FIGO grade 1-2 EC with evidence of extrauterine disease on imaging (CT, MRI, or PET)
- ✓ Postoperatively:
- ✓ Endometrial cancer (FIGO) with one or more established risk factors:
You may not qualify if…
- ✕ Patient receiving or who has received neoadjuvant chemotherapy
- ✕ Pre-operative pregnancy
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT07062016 · last updated 2026-04-13