RecruitingAfibSleep Apnea Syndrome, ObstructiveCPAP
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
Eligible age
18–85 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
No
See if you qualify for this study
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About this study
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe obstructive sleep apnea (OSA).
Sponsor: The Cleveland Clinic
You may qualify if…
- ✓ 1. Informed consent
- ✓ 2. Age 18-85 years
- ✓ 3. High burden paroxysmal AF (≥1%)
- ✓ 4. Moderate-severe OSA (AHI ≥ 15)
- ✓ 5. Implanted device with atrial diagnostics
- ✓ 6. Enrolled in remote monitoring
You may not qualify if…
- ✕ 1. AF ablation \<6 months
- ✕ 2. Valvular abnormalities
- ✕ 3. Excessive daytime sleepiness in safety-critical jobs
- ✕ 4. Plans for ablation during study
- ✕ 5. Non-CPAP OSA treatment
- ✕ 6. Recent device implantation (\<6 months)
- ✕ 7. Central sleep apnea
Where it's recruiting
Ohio
Cleveland
Washington
Seattle
Source: ClinicalTrials.gov · NCT07087587 · last updated 2026-04-13