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RecruitingHypertensionUncontrolled Hypertension

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

Eligible age

18–65 yrs

Accepts

All genders

Locations

17 states

Healthy volunteers

No

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About this study

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Iloperidone for the Treatment of Participants with Uncontrolled Hypertension

Sponsor: Vanda Pharmaceuticals

You may qualify if…

  • SiSBP \>/= 130 mmHg despite \>8 weeks treatment w/ 1 or more antihypertensive therapies

You may not qualify if…

  • Confirmed Grade 3/severe hypertension (SiSBP \>/= 180 mmHg, SiDBP \>/= 120 mmHg), unstable cardiac disease, renal insufficiency

Where it's recruiting

Arizona

Phoenix · Tempe · Tucson

California

Chula Vista · Dublin · Valencia · Walnut Creek

Florida

Doral · Fort Myers

Georgia

Columbus

Illinois

Oak Brook · Tinley Park

Kansas

El Dorado · Wichita

Kentucky

Lexington

Missouri

Hazelwood

Nevada

Las Vegas

New York

Mount Kisco · Rochester

Ohio

Cincinnati

Source: ClinicalTrials.gov · NCT07090161 · last updated 2026-02-27