RecruitingGlaucoma
Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The goal of this study is to see whether repeated transcranial alternating current stimulation can activate impaired retinal ganglion cells and improve both structural and functional outcomes in patients with glaucoma.
Sponsor: National Taiwan University Hospital
You may qualify if…
- ✓ 1. Participant must be at least 18.
- ✓ 2. Clinical diagnosis of glaucoma, with Humphrey Visual Field 24-2 mean deviation (MD) between -22 dB and -5 dB, and Visual Field Index (VFI) between 10% and 90%. The visual field test at screening must meet the following reliability indices:
- ✓ Fixation losses (FL) ≤ 33%
- ✓ False-negative rate (FNR) ≤ 20%
- ✓ False-positive rate (FPR) ≤ 20% At initial screening, the difference in MD between two consecutive visual field tests must be less than 2 dB.
- ✓ 3. Best-corrected visual acuity (BCVA) ≥ 0.2 in the worse eye selected for stimulation treatment.
- ✓ 4. If a participant has two eyes meeting study criteria, one eye will be randomly selected by computer for study participation.
- ✓ 5. In the opinion of the investigator the participant's eye pressure must be clinically stable.
You may not qualify if…
- ✕ 1. History of ocular herpes.
- ✕ 2. Pathological nystagmus.
- ✕ 3. Retinal disease sufficient to affect vision.
- ✕ 4. Corneal opacity affecting vision.
- ✕ 5. Cataract affecting vision.
- ✕ 6. Uveitis or other intraocular inflammatory disease.
- ✕ 7. Implanted electronic devices such as a pacemaker.
- ✕ 8. Rheumatologic or autoimmune disease.
Where it's recruiting
Hawaii
Taipei
Source: ClinicalTrials.gov · NCT07145073 · last updated 2026-01-30