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RecruitingChronic Obstructive Pulmonary Disease (COPD)Sedation and Analgesia

No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study

Eligible age

18+ yrs

Accepts

All genders

Locations

0 states

Healthy volunteers

No

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About this study

this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.

Sponsor: Benha University

You may qualify if…

  • Patients of both sex aged 18 years or older
  • The study will include 60 patients divided into 2 equal groups
  • Invasive mechanical ventilation
  • Patients with COPD patients (post-bronchodilator FEV1/FVC\< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.

You may not qualify if…

  • Allergy to sedative which will be used
  • renal or hepatic impairment
  • proven or suspected psychiatric or neurological impairment
  • pregnancy

Source: ClinicalTrials.gov · NCT07146698 · last updated 2025-09-11