Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
Eligible age
18+ yrs
Accepts
All genders
Locations
3 states
Healthy volunteers
No
See if you qualify for this study
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About this study
By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to learn how best to match the right type and amount of treatment to each individual veteran. By conducting this research project, they hope to: * See if trying a different treatment strategy for veterans not responding to their first PTSD treatment would be more helpful * See if sending text message prompts between sessions encourages more completion of between-session homework
Sponsor: The University of Texas Health Science Center at San Antonio
You may qualify if…
- ✓ 1. Veterans eligible for PE and CPT at the participating PTSD treatment-providing clinic who are
- ✓ 2. At least 18 years or older
- ✓ 3. Score ≥ 31 on the PCL-5 secondary to a Criterion A traumatic event
- ✓ 4. Own a mobile device that can be used for the therapy companion mobile app (Prolonged Exposure (PE) coach or Cognitive Processing Therapy (CPT) coach).
You may not qualify if…
- ✕ 1. Acute suicide risk requiring clinical intervention
- ✕ 2. Need for detoxification
- ✕ 3. Unmanaged psychosis or bipolar disorder
- ✕ 4. Severe cognitive impairment that makes it unlikely that participants can adhere to the study regimen (as evidenced by confusion, inability to track discussion or answer questions, or other clear and significant indicators of cognitive impairment)
- ✕ 5. Current or past 12-month engagement in PE or CPT.
Where it's recruiting
Source: ClinicalTrials.gov · NCT07176273 · last updated 2025-12-19