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RecruitingObstructive Sleep Apnea (OSAS)Obstructive Sleep Apnea (SAOS)

Home-based Under Mattress Monitor for OSA

Eligible age

18–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The aim of the study is to evaluate the effectiveness of the under-mattress monitoring device to aid in the titration process of a mandibular advancement device (MAD) for the management of obstructive sleep apnea (OSA). A secondary aim is to evaluate changes in subjective OSA symptoms and patient's satisfaction with MAD. A third aim is to analyze if there are differences between the sleep parameters recorded by the under-mattress monitor between responders and non-responders to MAD therapy.

Sponsor: Isabel Moreno Hay

You may qualify if…

  • Diagnosis of Obstructive Sleep Apnea demonstrated with a sleep study polysomnography or home sleep study (PSG or HSAT), manually scored by a sleep physician according to the 2017 American Academy of Sleep medicine scoring guidelines.
  • Willingness to commute to the OFP clinic every 2 weeks during MAD titration period.
  • Consent to partake in the study.

You may not qualify if…

  • Diagnosis of central or mixed sleep apnea.
  • Neurocognitive disease.
  • Concomitant therapy with PAP therapy.
  • Allergic to the appliance material (Polyamide 12).
  • Presence of active dental decay, ill-fitting dental restorations, or crown to root ratio unfavorable.
  • Inadequate English language comprehension.
  • Lack of coordination or dexterity to insert/remove the MAD intraorally.
  • Inability to tolerate digital dental impressions.

Where it's recruiting

Kentucky

Lexington

Source: ClinicalTrials.gov · NCT07186725 · last updated 2026-02-03