RecruitingMajor Depressive Disorder (MDD)Suicidal IdeationHospitalization in Children
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Eligible age
14–18 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
Sponsor: Children's Hospital Medical Center, Cincinnati
You may qualify if…
- ✓ 1. Fluent in English and able to volunteer in the informed consent process and provide spontaneous narrative description of key elements, risks, and benefits of the study.
- ✓ 2. Aged 14 years to 18 years, inclusive.
- ✓ 3. Diagnosis of MDD based on psychologist diagnosis and DSM-5-checklist based interview.
- ✓ 4. Symptoms of moderate to severe depression according to Hamilton Depression Rating Scale Score \> 20.
- ✓ 5. Participants are not required to discontinue current interventions
You may not qualify if…
- ✕ 1. Participation in an investigational drug trial within the past three months.
- ✕ 2. Contraindications to Transcranial Magnetic Stimulation including, but not limited to, a history of epilepsy, the presence of metallic foreign bodies, or implanted medical devices (e.g. ventriculoperitoneal shunt, pacemaker, medical pump).
- ✕ 3. Actively psychotic (i.e. disorganized, delusional, paranoid, or having hallucinations)
- ✕ 4. Actively suicidal (have a suicidal plan and intent and is on 1:1 close observation)
- ✕ 5. For female subjects of childbearing potential, a positive urine pregnancy test.
Where it's recruiting
Ohio
Cincinnati
Source: ClinicalTrials.gov · NCT07217444 · last updated 2026-02-11