RecruitingAsthma

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

Eligible age

18–75 yrs

Accepts

All genders

Locations

11 states

Healthy volunteers

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

Check my eligibility →

About this study

The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

Sponsor: Eli Lilly and Company

You may qualify if…

✓ Physician-diagnosed asthma who have received a physician-prescribed asthma controller medication for at least 12 months prior to screening visit.
✓ Participants must have an asthma control questionnaire-6 (ACQ-6) score of ≥1.5 on 2 out of 3 visits before randomization.
✓ History of 1 severe asthma exacerbation that led to systemic glucocorticoid treatment in the last 12 months prior to screening visit.

You may not qualify if…

✕ Participants are excluded from the study if any of the following criteria apply:
✕ An established diagnosis of occupational asthma
✕ Known pre-existing, clinically important lung condition other than asthma, including but not limited to:
✕ chronic respiratory infection
✕ bronchiectasis
✕ pulmonary fibrosis
✕ allergic bronchopulmonary aspergillosis
✕ emphysema