RecruitingHematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
This clinical trial tests the feasibility, best dose, and effectiveness of L-theanine for supporting relaxation and mood among cancer patients in surveillance. L-theanine is a substance found in the leaves of green tea with potential to enhance mental health and well-being. It works by increasing certain chemicals within the body that have been associated with stress reduction, mood stabilization, and improved cognitive performance.
Sponsor: City of Hope Medical Center
You may qualify if…
- ✓ Documented informed consent of the participant and/or legally authorized representative.
- ✓ Assent, when appropriate, will be obtained per institutional guidelines
- ✓ Willingness to comply with all study interventions including the use of L-theanine and follow-up assessments
- ✓ Age: ≥ 18 years
- ✓ Ability to read and understand English or Spanish for questionnaires
- ✓ Patients must be a cancer patient who has completed treatment and has been in surveillance for at least 6 months
- ✓ Participants must not have used any herbs or supplements in the past 30 days
- ✓ Participants must report an anxiety score of \> 3 on Visual Analog Scale - Anxiety
You may not qualify if…
- ✕ Concurrent use of other alternative medicines, including herbal agents and high-dose vitamins and minerals, unless taken to correct a documented vitamin or mineral insufficiency
- ✕ Chemotherapy, radiation therapy, biological therapy, immunotherapy, or any other systemic treatment excluding hormonal therapy (must be on a stable dose of hormonal therapy for at least 60 days)
- ✕ Any patients taking bortezomib, as L-theanine can decrease effectiveness
- ✕ Any patients currently enrolled in other clinical trials that might interfere with the results of this study
- ✕ History of allergic reactions attributed to compounds of similar chemical or biologic composition to study agent
- ✕ Any patients with an ongoing active/unstable psychiatric condition, depressive/bi-polar related disorders, anxiety, psychosis disorders, or substance use that may interfere with the ability to participate in the study as outlined in the study procedures section of the protocol
- ✕ Any patients with chronically unstable blood pressure or chronic low blood pressure
- ✕ Diagnosis of Gilbert's disease
Where it's recruiting
California
Duarte · Huntington Beach · Irvine
Source: ClinicalTrials.gov · NCT07220447 · last updated 2026-05-08