Cardiometabolic Effects of Pecan Snacking in Prediabetes
Eligible age
25–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The purpose of this study is to investigate the effects of replacing snacks higher in saturated fats and added sugars with pecans on blood sugar control, heart health and diet quality in individuals with prediabetes. Participants will be randomized into one of two groups. Group 1 will consume 1.5 oz of pecans per day in place of normally consumed snacks higher in saturated fat and added sugars for 16 weeks. Group 2 will be asked to continue consuming their current diet for 16 weeks. Measures will be taken to evaluate blood sugar, heart health and dietary intake at the beginning and 16 weeks later.
Sponsor: Penn State University
You may qualify if…
- ✓ Age 25-65 years
- ✓ Prediabetes assessed by an HbA1c of 5.7-6.4% at screening
- ✓ BMI 25-40 kg/m2 at screening
- ✓ Low habitual nut consumption (\<3.5 oz-eq/week) assessed at the telephone screening
- ✓ Regularly eats snacks higher in saturated fat and/or added sugars assessed at the telephone screening
You may not qualify if…
- ✕ LDL-C ≥190 mg/dL at screening
- ✕ Hemoglobin \<13.2 g/dL at screening
- ✕ Fasting triglycerides \>350 mg/dL at screening
- ✕ ≥10% change in body weight within the 6 months prior to enrollment
- ✕ Blood pressure \>140/90 mmHg at screening
- ✕ Type 1 or type 2 diabetes
- ✕ Prescription of anti-hypertensive, lipid-lowering, or glucose-lowering drugs
- ✕ Intake of supplements or over-the-counter medications that affect the outcomes of interest (i.e., lipid, blood pressure, or glucose lowering; vitamin C or multi-vitamins containing vitamin C) and are unwilling to cease during the study period.
Where it's recruiting
University Park
Source: ClinicalTrials.gov · NCT07235358 · last updated 2026-05-27