RecruitingObesity
PRImary Care Strategies for Weight Management (PRISM) Study
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The goal of this clinical trial pilot is to determine the feasibility of an intervention to enhance weight management in patients who have stopped taking anti-obesity/weight management medications in primary care. The main questions it aims to answer are: * Can patients be recruited into the study efficiently? * Is the program acceptable to patients? * Can the study be conducted efficiently? The new program will be compared to usual care.
Sponsor: Rush University Medical Center
You may qualify if…
- ✓ 1. For run-in: prescribed liraglutide, semaglutide, or tirzepatide or newer medication approved by the FDA for long-term use for obesity treatment for the purpose of weight managment by a primary care provider at Rush University System for Health and have received at least one dose of the medication concurrent with enrollment in the study.
- ✓ 2. For randomization: discontinue their prescribed anti-obesity medication.
- ✓ 3. Age 18+
You may not qualify if…
- ✕ 1. Not fluent in English
- ✕ 2. Diagnosis of diabetes (type 1 or type 2)
- ✕ 3. Current or planned pregnancy
- ✕ 4. Bariatric surgery in the past 2 years or planned bariatric surgery.
- ✕ 5. Body mass index ≥60 kg/m2, due to increased injury risk with exercise
- ✕ 6. Body weight ≥ 375 pounds (scale capacity with a margin for regain)
- ✕ 7. No access to home WIFI or a smartphone with data available
- ✕ 8. Medical contraindications to treatment, including significant cognitive impairment, active substance abuse based on the World Health Organization's ASSIST screener, or serious medical illness (e.g., stage 3 or 4 heart failure, cancer, renal failure, etc.)
Where it's recruiting
Illinois
Chicago
Source: ClinicalTrials.gov · NCT07288294 · last updated 2026-07-09