RecruitingIschemic Stroke
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this study is to evaluate the safety, feasibility, and efficacy of vagus nerve stimulation (VNS) paired with mobility training to improve lower extremity function and gait in individuals with chronic ischemic stroke.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ Age ≥ 18 years
- ✓ Ischemic stroke ≥6 months prior to enrollment.
- ✓ Post-stroke lower extremity impairment defined as gait velocity of less than 0.8 m/s on a 10-meter walk test
- ✓ Provision of informed consent
You may not qualify if…
- ✕ Intracerebral Hemorrhage
- ✕ Active or prior psychosis or substance abuse within two years.
- ✕ Pre-stroke modified Rankin Scale (mRS) 3-5.
- ✕ Unable to participate in in-clinic rehabilitation.
- ✕ Preexisting neurological disorders affecting gait and mobility, such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), dementia, major head trauma.
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT07291024 · last updated 2026-02-17