Myofunctional Therapy for Obstructive Sleep Apnea
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The purpose of this study is to explore a new way to examine the function of the muscles using a technique called high-resolution manometry. The study will enroll 30 adults with OSA, all of whom will use the myofunctional therapy (MFT) devices for 3 months. High-resolution manometry will be used to measure the amount of pressure generated by the muscles of the throat when drinking water or breathing air, both with and without the MFT devices, and before and after the MFT intervention. If successful, this method can help us understand why sleep improves after MFT.
Sponsor: University of Minnesota
You may qualify if…
- ✓ Adults aged 18-65
- ✓ New diagnosis of OSA (AHI ≥ 5) or failure of first-line OSA treatment
- ✓ Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months
You may not qualify if…
- ✕ Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia)
- ✕ Severe nasal obstruction
- ✕ Severe ankyloglossia
- ✕ Craniofacial abnormality
- ✕ Severe pulmonary disease
- ✕ Severe post-traumatic stress disorder (PCL-5 \> 33)
- ✕ Very severe insomnia (ISI \> 22)
- ✕ Body mass index (BMI) ≥30 kg/m2.
Where it's recruiting
Minneapolis
Source: ClinicalTrials.gov · NCT07301125 · last updated 2026-06-18