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RecruitingObesityOverweight

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

Eligible age

18+ yrs

Accepts

All genders

Locations

23 states

Healthy volunteers

No

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About this study

The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a main phase and an extension phase. Participation in the main phase of the study will last about 75 weeks. Participants with prediabetes will continue in the extension phase for another 2 years.

Sponsor: Eli Lilly and Company

You may qualify if…

  • Have Body Mass Index (BMI) at screening of the following:
  • 30 kilogram per square meter (kg/m2) OR
  • 27 kg/m2 with at least one of the following weight-related health conditions at screening:
  • high blood pressure
  • dyslipidemia
  • obstructive sleep apnea, or
  • heart disease
  • Have a stable body weight (\<5% body weight change) for 90 days prior to screening.

You may not qualify if…

  • Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed \>1 year before screening)
  • Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening)
  • Have type 1 diabetes or type 2 diabetes
  • Have had within 90 days prior to screening:
  • heart attack
  • stroke
  • coronary artery revascularization
  • unstable angina, or

Where it's recruiting

Alabama

Tuscaloosa

Arizona

Scottsdale

California

Escondido · Fountain Valley · Palm Springs · Rolling Hills Estates

Connecticut

Waterbury

Florida

Atlantis · Miami · Mt. Dora · Pembroke Pines

Georgia

Dunwoody · Lawrenceville · Stockbridge

Hawaii

Honolulu

Iowa

West Des Moines

Kansas

Topeka

Louisiana

Lake Charles

Maryland

Baltimore · Hyattsville

Source: ClinicalTrials.gov · NCT07321886 · last updated 2026-06-23