A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eligible age
18+ yrs
Accepts
All genders
Locations
23 states
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a main phase and an extension phase. Participation in the main phase of the study will last about 75 weeks. Participants with prediabetes will continue in the extension phase for another 2 years.
Sponsor: Eli Lilly and Company
You may qualify if…
- ✓ Have Body Mass Index (BMI) at screening of the following:
- ✓ 30 kilogram per square meter (kg/m2) OR
- ✓ 27 kg/m2 with at least one of the following weight-related health conditions at screening:
- ✓ high blood pressure
- ✓ dyslipidemia
- ✓ obstructive sleep apnea, or
- ✓ heart disease
- ✓ Have a stable body weight (\<5% body weight change) for 90 days prior to screening.
You may not qualify if…
- ✕ Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed \>1 year before screening)
- ✕ Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening)
- ✕ Have type 1 diabetes or type 2 diabetes
- ✕ Have had within 90 days prior to screening:
- ✕ heart attack
- ✕ stroke
- ✕ coronary artery revascularization
- ✕ unstable angina, or
Where it's recruiting
Tuscaloosa
Scottsdale
Escondido · Fountain Valley · Palm Springs · Rolling Hills Estates …
Waterbury
Atlantis · Miami · Mt. Dora · Pembroke Pines …
Dunwoody · Lawrenceville · Stockbridge
Honolulu
West Des Moines
Topeka
Lake Charles
Baltimore · Hyattsville
Quincy
Source: ClinicalTrials.gov · NCT07321886 · last updated 2026-06-23