RecruitingCognitive DysfunctionCognitive Decline
Broccoli Sprout Extract for Cognitive Function
Eligible age
50–85 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
This clinical trial aims to determine whether broccoli sprout extract improves cognitive function in adults with mild cognitive impairment and to assess its safety. The main questions are: * Does broccoli sprout extract improve cognitive function in participants? * What side effects occur when participants take broccoli sprout extract?
Sponsor: Pusan National University Yangsan Hospital
You may qualify if…
- ✓ Age: Adults aged 55-85 years (inclusive), both male and female
- ✓ Global Deterioration Scale (GDS) score of 2-3:
- ✓ GDS 2: Subjective memory impairment without objective evidence GDS 3: Mild objective memory impairment
- ✓ Absence of dementia according to established diagnostic criteria
- ✓ Ability to read Korean
You may not qualify if…
- ✕ Severe medical conditions within the past 6 months: History of severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage), cardiac disease (angina, myocardial infarction, heart failure, arrhythmia requiring treatment), or malignancy (Note: Participants with a history of cerebrovascular or cardiac disease who are clinically stable may be included at the investigator's discretion)
- ✕ Cognitive impairment-associated diseases: Dementia, Parkinson's disease, cerebral infarction, or other conditions associated with cognitive decline Uncontrolled hypertension: Blood pressure ≥160/100 mmHg (measured after 10 minutes of rest)
- ✕ Poor glycemic control: Fasting blood glucose ≥160 mg/dL in diabetic patients
- ✕ Uncontrolled thyroid dysfunction: Currently receiving treatment for uncontrolled hypothyroidism or hyperthyroidism
- ✕ Renal impairment: Serum creatinine ≥2 times the upper limit of normal for the institution
- ✕ Hepatic impairment: AST or ALT ≥2 times the upper limit of normal for the institution
- ✕ Severe gastrointestinal symptoms: Complaints of severe heartburn, dyspepsia, or other gastrointestinal distress
- ✕ Medications affecting cognitive function within the past month: Use of drugs (antipsychotics, anti-degenerative agents, cognitive enhancers, tricyclic antidepressants, hormone replacement therapy) or health functional foods that may influence cognitive function due to dementia or other cognitive abnormalities
Source: ClinicalTrials.gov · NCT07334366 · last updated 2026-01-13