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RecruitingTransthyretin Amyloidosis With Cardiomyopathy

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Eligible age

18+ yrs

Accepts

All genders

Locations

12 states

Healthy volunteers

No

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About this study

The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care * Describe treatment patterns of adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess health-related quality of life (HRQOL) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess healthcare resource use (HCRU) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Compare the long-term effectiveness of vutrisiran versus other approved ATTR-CM treatments in routine clinical care

Sponsor: Alnylam Pharmaceuticals

You may qualify if…

  • ✓ Has a diagnosis of ATTR-CM
  • ✓ Is initiating treatment with vutrisiran or another approved ATTR-CM therapy

You may not qualify if…

  • ✕ Is enrolled in an interventional clinical trial

Where it's recruiting

Arizona

Tucson

California

Beverly Hills · La Jolla

Florida

Naples

Hawaii

Honolulu

Kansas

Kansas City

Missouri

St Louis

New Jersey

New Brunswick

Pennsylvania

Philadelphia

Tennessee

Memphis

Texas

Dallas

Source: ClinicalTrials.gov · NCT07358078 · last updated 2026-10-09

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