RecruitingHypertensionPostpartum Preeclampsia
Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
To determine if nifedipine and enalapril will have better blood pressure control in the postpartum setting compared to nifedipine and labetalol.
Sponsor: The Cleveland Clinic
You may qualify if…
- ✓ Postpartum women aged 18 years or older
- ✓ Clinical diagnosis of hypertensive disorder in pregnancy (gestational hypertension, chronic hypertension, preeclampsia with or without severe features)
- ✓ Taking Nifedipine 60 mg every 12 hours for blood pressure control
- ✓ Persistently elevated blood pressure at/above 140/90 mmHg in a 24-hour time period or have one or more severe range blood pressure at/above 160/110 mmHg requiring a second antihypertensive medication
- ✓ English speaking
You may not qualify if…
- ✕ Taking ≥2 antihypertensive agents during pregnancy
- ✕ Heart block
- ✕ Heart rate \<60 or \>120 beats per minute
- ✕ Heart failure
- ✕ Creatinine \>1.5 mg/dL
- ✕ Renal artery stenosis
- ✕ Active connective tissue disease
- ✕ Cerebrovascular accident
Where it's recruiting
Ohio
Cleveland
Source: ClinicalTrials.gov · NCT07363343 · last updated 2026-08-03