Effect of Combined Quadriceps and Calf Strengthening Program on Gait in Knee Osteoarthritis Patients
Eligible age
40–60 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
The aim of this study is to determine the effects of a combined quadriceps and calf strengthening program on gait, strength, pain, disability, functional mobility, and sleep quality in patients with knee osteoarthritis. A randomized controlled trial will be conducted at Hayatabad Medical Complex, Peshawar. A total of 52 participants aged 40-60 years with grade 2-3 knee osteoarthritis will be recruited using non-probability convenience sampling and randomly allocated into experimental and control groups. Outcome measures include Kinovea software for gait analysis, hand-held dynamometer for strength, Numeric Rating Scale for pain, WOMAC for disability, Timed Up and Go test for function, and Pittsburgh Sleep Quality Index for sleep quality. Data will be analyzed using SPSS version 27 employing repeated measures ANOVA and mixed-way ANOVA.
Sponsor: Riphah International University
You may qualify if…
- ✓ Both Male and Female
- ✓ Participants aged 40-60years.
- ✓ Diagnosed with grade 2 and 3 of knee osteoarthritis according to Kellgren-Lawrence
- ✓ Quads manual muscle grading \<4
- ✓ Ability to understand and comply with exercise instructions.
You may not qualify if…
- ✕ History of recent knee surgery or trauma in the past six months.
- ✕ Inflammatory joint diseases (e.g., rheumatoid arthritis, gout).
- ✕ Severe cardiovascular or neurological disorders.
- ✕ Uncontrolled hypertension or diabetes.
- ✕ Participation in other physiotherapy or pharmacological interventions for knee OA during the study period.
- ✕ Cognitive impairment or inability to follow commands
Source: ClinicalTrials.gov · NCT07402447 · last updated 2026-09-09